SCHEMBL11217062

SCHEMBL11217062

CCOC(=O)C1CCCCC1C(=O)Cc1ccccc1CC#N

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 6/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
MAPT P10636 2/20 0.38
PKM P14618 1/20 0.38
MAPK1 P28482 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
ATM Q13315 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4579114 0.75 PKM (0.49) ALDH1A1KDM4ESMN1; SMN2MAPTPKM
SCHEMBL6209497 0.74 ATM (0.43) ALDH1A1SMN1; SMN2MAPTPKMATM
SCHEMBL20924718 0.72 TSHR (0.52) ALDH1A1MAPTPKMNPSR1
SCHEMBL14382020 0.71 ATM (0.42) ALDH1A1KDM4ESMN1; SMN2MAPTPKM
SCHEMBL7103767 0.71 MAPT (0.41) ALDH1A1KDM4ESMN1; SMN2MAPTPKM
SCHEMBL6900183 0.71 TP53 (0.53) ALDH1A1MAPTATMMEN1KMT2A
SCHEMBL13011542 0.71 TP53 (0.53) ALDH1A1MAPTATMMEN1KMT2A
SCHEMBL234644 0.71 TP53 (0.53) ALDH1A1MAPTATMMEN1KMT2A
SCHEMBL28405577 0.71 TP53 (0.53) ALDH1A1MAPTATMMEN1KMT2A
SCHEMBL6928309 0.70 ALDH1A1 (0.49) ALDH1A1KDM4ESMN1; SMN2MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338122-A MITICIDES, HERBICIDES UNION CARBIDE CORPORATION (US) 1982-07-06 US disclosed
US-4283348-A SODIUM ETHOXIDE PROMOTED CYCLIZATION OF LEVULINIC ACID ESTERS UNION CARBIDE CORPORATION (US) 1981-08-11 US disclosed