Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812203 | 0.82 | ATM (0.41) | ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A | |
| SCHEMBL8022828 | 0.78 | TP53 (0.39) | KDM4EKMT2AMEN1POLBTAS1R3 | |
| SCHEMBL14382020 | 0.77 | ATM (0.42) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL8708085 | 0.76 | POLB (0.40) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL1814587 | 0.75 | TAS1R3 (0.52) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL7103767 | 0.74 | MAPT (0.41) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL31514215 | 0.74 | NLRP3 (0.54) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL2687043 | 0.74 | TAS1R3 (0.36) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3174224 | 0.73 | TAS1R3 (0.35) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1476733 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4ETDP1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569810-B1 | (2-alkoxycarbonylcyclohexyl) (substituted benzyl) ketones of given formula; insecticidal, acaricidal and herbicidal action | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-27 | — | — | US | disclosed |
| US-6515184-B1 | The present invention relates to novel bicyclic cyclopentane-1,3- dione derivatives of the formula (I) to a process for their preparation and to their use as pesticides and herbicides. | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-04 | — | — | US | disclosed |
| EP-0854852-B1 | CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 2001-10-17 | — | — | EP | disclosed |