SCHEMBL11217698

SCHEMBL11217698

Cc1cc(C)c(C2C(=O)CCC2=O)c([N+](=O)[O-])c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.44
TSHR P16473 4/20 0.41
CYP3A4 P08684 3/20 0.41
KDM4E B2RXH2 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
ALDH1A1 P00352 6/20 0.38
RECQL P46063 1/20 0.38
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
GAA P10253 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL986581 0.80 UGT2B17 (0.33) KDM4EGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11217395 0.80 ALDH1A1 (0.47) GPR35TSHRCYP3A4KDM4EALDH1A1
SCHEMBL10729507 0.73 UGT2B17 (0.35) KDM4EGAATDP1HSD17B10
SCHEMBL19549149 0.73 LMNA (0.36) ALDH1A1MAPT
SCHEMBL11222751 0.72 TSHR (0.49) GPR35TSHRALDH1A1MAPTL3MBTL1
SCHEMBL349045 0.70 GPR35 (0.55) GPR35TSHRCYP3A4KDM4EGRIN2D
SCHEMBL29816776 0.70 GPR35 (0.55) GPR35TSHRCYP3A4KDM4EGRIN2D
SCHEMBL8977884 0.69 GPR35 (0.59) GPR35TSHRCYP3A4KDM4EGRIN2D
SCHEMBL9719276 0.67 GPR35 (0.57) GPR35TSHRCYP3A4KDM4EGRIN2D
SCHEMBL2232801 0.67 GPR35 (0.61) GPR35TSHRCYP3A4KDM4EGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338122-A MITICIDES, HERBICIDES UNION CARBIDE CORPORATION (US) 1982-07-06 US disclosed
US-4283348-A SODIUM ETHOXIDE PROMOTED CYCLIZATION OF LEVULINIC ACID ESTERS UNION CARBIDE CORPORATION (US) 1981-08-11 US disclosed