Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816776 | 1.00 | GPR35 (0.55) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL2232801 | 0.89 | GPR35 (0.61) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL30040348 | 0.83 | ALDH1A1 (0.60) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL9107706 | 0.83 | ALDH1A1 (0.60) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL7786697 | 0.83 | TSHR (0.60) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL6672266 | 0.82 | ALDH1A1 (0.63) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL153660 | 0.82 | ALDH1A1 (0.48) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL2970574 | 0.82 | ALDH1A1 (0.63) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL1285944 | 0.80 | ALDH1A1 (0.47) | GPR35TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL3296412 | 0.80 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4RECQLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707829-A | 2-Phenyl-benzo nitrogen-containing heterocyclic compound, and preparation method and application thereof | 合肥大学 | 2025-03-28 | — | — | CN | claimed |
| CN-117430967-A | High-dispersity permanent orange RN and preparation method and application thereof | 济宁阳光化学有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-114621096-A | Synthetic method of 3, 5-dimethyl-1, 2-phenylenediamine dihydrochloride | 余购粮 | 2022-06-14 | — | — | CN | claimed |
| CN-105606605-A | Para hydroxybenzene alanine urine detection kit and preparation method thereof | ZHANG FENGHUA | 2016-05-25 | — | — | CN | claimed |
| US-6372030-B1 | INK VEHICLE SELECTED FROM 4-(HEXADECYLAMINO)BENZYLAMINE, N-OCTANOYL-N-METHYL GLUCAMINE, OCTANOIC HYDRAZIDE, 4-HEXADECYL SULFONYL ANILINE, A CONDUCTIVE COMPLEX OF AN AMINE COMPOUND WITH A PHOSPHORUS OR SULFUR-CONTAINING ACID | XEROX CORPORATION | 2002-04-16 | — | — | US | claimed |
| US-12486248-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-02 | — | — | US | disclosed |
| US-12391663-B2 | Isoindolinone compounds | MONTE ROSA THERAPEUTICS AG (CH) | 2025-08-19 | — | — | US | disclosed |
| CN-119707829-A | 2-Phenyl-benzo nitrogen-containing heterocyclic compound, and preparation method and application thereof | 合肥大学 | 2025-03-28 | — | — | CN | disclosed |
| US-20250101052-A1 | COMPOUND FOR EGFR KINASE INHIBITOR, COMPOSITION, AND USE THEREOF | INNOVATION INSTITUTE FOR ARTIFICIAL INTELLIGENCE IN MEDICINE OF ZHEJIANG UNIVERSITY (CN) | 2025-03-27 | — | — | US | disclosed |
| US-20240261274-A1 | TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS | MONTE ROSA THERAPEUTICS AG (CH) | 2024-08-08 | — | — | US | disclosed |
| US-20240083869-A1 | ISOINDOLINONE COMPOUNDS | MONTE ROSA THERAPEUTICS AG (CH) | 2024-03-14 | — | — | US | disclosed |
| US-11912682-B2 | Isoindolinone compounds | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-4138570-A | METHINE DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |
| US-4085268-A | Disubstituted s-triazines | ARMSTRONG CORK COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4038268-A | DIAZOTIZATION, COUPLING | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4006128-A | CELLULOSE ACETATES, VINYL POLYMERS, POLYOLEFINS, POLYESTERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
| US-4003875-A | ULTRAVIOLET ABSORBERS | CIBA-GEIGY CORPORATION (US) | 1977-01-18 | — | — | US | disclosed |
| US-3957749-A | WATER-INSOLUBLE MONOAZO PYRIDINE DYES | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3934019-A | FUNGICIDE, INSECTICIDE, MITICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391663-B2 | Isoindolinone compounds | CYP4F2, AOC2, AOC3 | GPR35 3797/4885TSHR 1114/4885ALDH1A1 1142/4885 |
| US-20240083869-A1 | ISOINDOLINONE COMPOUNDS | CYP4F2, AOC2, AOC3 | GPR35 3797/4885TSHR 1114/4885ALDH1A1 1142/4885 |
| US-20250101052-A1 | COMPOUND FOR EGFR KINASE INHIBITOR, COMPOSITION, AND USE THEREOF | EGFR, ERBB2, ERBB3 | GPR35 1915/4885TSHR 973/4885ALDH1A1 2593/4885 |
| US-12486248-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | DHODH, DHPS, DPYD | GPR35 3063/4885TSHR 3994/4885ALDH1A1 132/4885 |
| US-11912682-B2 | Isoindolinone compounds | CYP4F2, AOC2, AOC3 | GPR35 3797/4885TSHR 1114/4885ALDH1A1 1142/4885 |
| US-20240261274-A1 | TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS | MYC, MYCBP, GSPT1 | GPR35 2597/4885TSHR 2333/4885ALDH1A1 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.