Methacrylic Acid

Methacrylic Acid

SCHEMBL11217872

C=C(C)C(=O)O.C=C(C)C(=O)OC.C=CC(=O)OC(CC)CCCCC

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.35
CTSK P43235 3/20 0.34
ZDHHC7 Q9NXF8 1/20 0.33
CTSL P07711 1/20 0.32
CTSB P07858 1/20 0.32
PRKCA P17252 1/20 0.32
PRKCD Q05655 1/20 0.32
ABCB1 P08183 1/20 0.32
GLS2 Q9UI32 2/20 0.32
THRB P10828 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
PLA2G2C Q5R387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5336277 0.96 ALDH1A1 (0.41) TSHRALDH1A1HPGDCTSKZDHHC7
Methacrylic Acid SCHEMBL16932495 0.92 TSHR (0.43) TSHRHPGDCTSKCTSLCTSB
SCHEMBL29362857 0.88 TSHR (0.42) TSHRHPGDCTSKZDHHC7CTSL
Styrene SCHEMBL2351978 0.87 CTSK (0.39) ALDH1A1CTSKCTSLCTSBTHRB
SCHEMBL9777346 0.86 TSHR (0.35) TSHRHPGDCTSKZDHHC7CTSL
Methacrylic Acid SCHEMBL27677740 0.85 TSHR (0.44) TSHRHPGDCTSKGLS2THRB
SCHEMBL16333632 0.85 TSHR (0.40) TSHRALDH1A1HPGD
SCHEMBL8620233 0.85 TSHR (0.44) TSHRALDH1A1HPGDCTSKZDHHC7
SCHEMBL8501557 0.84 TSHR (0.51) TSHRALDH1A1HPGDCTSKPRKCA
SCHEMBL5058155 0.84 TSHR (0.34) TSHRHPGDCTSKZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57098512-A None JP disclosed
JP-S5798512-A PRODUCTION OF HYDROGEL SUMITOMO CHEM CO LTD 1982-06-18 JP disclosed