Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869926 | 0.87 | TAS1R3 (0.35) | TPMT | |
| SCHEMBL16688213 | 0.86 | RAPGEF4 (0.33) | TPMT | |
| SCHEMBL570091 | 0.86 | CES2 (0.41) | CYP3A4MEN1PLA2G1BCYP1A2GAA | |
| SCHEMBL2010985 | 0.86 | NOTUM (0.31) | TPMT | |
| SCHEMBL24145139 | 0.86 | TPMT (0.30) | TPMT | |
| SCHEMBL2033922 | 0.84 | TPMT (0.39) | TPMTTSHRRAB9ACYP3A4MEN1 | |
| SCHEMBL15195896 | 0.82 | AHR (0.33) | RAB9AAHR | |
| SCHEMBL14956056 | 0.82 | TPMT (0.38) | TPMTTSHRRAB9ACYP3A4MEN1 | |
| SCHEMBL113435 | 0.79 | HPGD (0.39) | TSHRCYP3A4AHR | |
| SCHEMBL112191 | 0.79 | PARP1 (0.47) | TSHRRAB9AGAACYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118652221-A | Isoxazoline compound and preparation and application thereof | 上海应用技术大学 | 2024-09-17 | — | — | CN | claimed |
| CN-115246825-B | Isoxazoline derivative containing amide structure, preparation method thereof and application of isoxazoline derivative as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-114907236-B | Aldoxime compound and preparation method and application thereof | 四川青木制药有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-115246795-B | Isoxazoline compound containing ether structure at 4-phenyl para-position, preparation method thereof and application thereof as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-116640100-A | Solid-phase synthesis method of fluororalrana | 河北圣雪大成制药有限责任公司 | 2023-08-25 | — | — | CN | claimed |
| CN-113759052-B | Method for detecting related substances in fluorine Lei Lana initiator | 丽珠集团新北江制药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-113899833-B | Determination of 1, 3-dichloro-5- (1-trifluoromethyl-vinyl) benzene by gas chromatography | 丽珠集团新北江制药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-113759044-B | Method for detecting fluorine Lei Lana starter by reversed-phase HPLC | 丽珠集团新北江制药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-116102511-A | Preparation method of high-purity fluorine Lei Lana intermediate | 河北圣雪大成制药有限责任公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116041212-A | Preparation and application of difluoro olefin ether and oxime ether derivatives | 安徽农业大学 | 2023-05-02 | — | — | CN | claimed |
| CN-115246826-A | Quaternary ammonium salt isoxazoline compound, preparation thereof and application thereof as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-115246795-A | Isoxazoline compound with 4-phenyl para-position containing ether structure, preparation thereof and application thereof as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-115246825-A | Isoxazoline derivative containing amide structure, preparation thereof and application of isoxazoline derivative as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-114907236-A | Aldoxime compound and preparation method and application thereof | 四川青木制药有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-114394946-A | Synthesis method of flurarana | 艾美科健（中国）生物医药有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-113899833-A | Determination of 1, 3-dichloro-5- (1-trifluoromethyl-vinyl) benzene by gas chromatography | 丽珠集团新北江制药股份有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-113773312-A | Novel isoxazoline derivative and preparation method and application thereof | 河南牧业经济学院 | 2021-12-10 | — | — | CN | claimed |
| CN-113759044-A | Method for detecting frainer initiator by reversed-phase HPLC | 丽珠集团新北江制药股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-113759052-A | Method for detecting related substances in frataxin initiator | 丽珠集团新北江制药股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-111308002-A | Method for detecting isoxazoline insecticide and impurities thereof | 丽珠集团新北江制药股份有限公司 | 2020-06-19 | — | — | CN | claimed |