Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013821 | 0.85 | CES1 (0.39) | MAPT | |
| SCHEMBL112183 | 0.79 | TPMT (0.41) | TSHRGAACYP2C19KMT2ARAB9A | |
| SCHEMBL27757220 | 0.78 | CES1 (0.52) | PARP1HTTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL24738862 | 0.77 | PARP1 (0.52) | PARP1TSHRALDH1A1HTTMAPT | |
| SCHEMBL1794480 | 0.76 | PARP1 (0.56) | PARP1TSHRALDH1A1HTTMAPT | |
| SCHEMBL29791495 | 0.76 | ACHE (0.58) | PARP1ALDH1A1HTTMAPTLMNA | |
| SCHEMBL116615 | 0.76 | C1S (0.47) | PARP1ALDH1A1HTTMAPTLMNA | |
| SCHEMBL111125 | 0.76 | ACHE (0.58) | PARP1ALDH1A1HTTMAPTLMNA | |
| SCHEMBL30461157 | 0.76 | CES2 (0.60) | TSHRALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL32000 | 0.76 | CES2 (0.60) | TSHRALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651191-B | Difluoromethyl oxime ether derivative and synthetic method thereof | 华南理工大学 | 2021-11-19 | — | — | CN | disclosed |
| US-20190144469-A1 | METHOD FOR PREPARING DIFLUOROALLYLBORONATE AND APPLICATION THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2019-05-16 | — | — | US | disclosed |
| CN-109651191-A | A kind of difluoromethyl oxime ether derivatives and its synthetic method | 华南理工大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-104277032-B | PESTICIDAL (HETERO) ARYLPYRROLIDINES | 拜耳作物科学公司 | 2017-04-12 | — | — | CN | disclosed |
| EP-3095780-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2016-11-23 | — | — | EP | disclosed |
| US-9271499-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9266830-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| CN-102639529-B | Isoxazoline derivative-based pesticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-19 | — | — | CN | disclosed |
| US-9055749-B2 | Insecticidal arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| CN-101652354-A | insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG DE | 2010-02-17 | — | — | CN | disclosed |
| EP-2148853-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-02-03 | — | — | EP | disclosed |
| WO-2009112275-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-09-17 | — | — | WO | disclosed |
| CN-101522672-A | Insecticidal isoxazolines | BAYER CROPSCIENCE AG (DE) | 2009-09-02 | — | — | CN | disclosed |
| WO-2009097992-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2009-08-13 | — | — | WO | disclosed |
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| CN-101351456-A | Isoxazolines for controlling invertebrate pests | DU PONT (US) | 2009-01-21 | — | — | CN | disclosed |
| WO-2008128711-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008122375-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | DDT, ITPR3, CYP51A1 | PARP1 4359/4885TSHR 846/4885ALDH1A1 261/4885 |
| US-20190144469-A1 | METHOD FOR PREPARING DIFLUOROALLYLBORONATE AND APPLICATION THEREOF | GABRA6, GABRP, GABBR2 | PARP1 4025/4885TSHR 455/4885ALDH1A1 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.