Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548034 | 0.97 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL51245 | 0.97 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL9548113 | 0.96 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL9548138 | 0.93 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Oxalic Acid SCHEMBL9548067 | 0.88 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL9548074 | 0.86 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL10820229 | 0.84 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL12284587 | 0.84 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL12284628 | 0.84 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL13067271 | 0.84 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57206652-A | — | — | None | — | — | JP | disclosed |
| JP-S57206652-A | SUBSTITUTED PHENYL ETHER DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 1982-12-18 | — | — | JP | disclosed |