Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548034 | 0.94 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL51245 | 0.94 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Oxalic Acid SCHEMBL9548067 | 0.94 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL9548113 | 0.93 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL11218388 | 0.93 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL9548074 | 0.88 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Oxalic Acid SCHEMBL9548020 | 0.84 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL10820229 | 0.81 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL12284587 | 0.81 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL12284628 | 0.81 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198587-A | Adrenergic Blocking Agents, Hypotensive Agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| US-5063246-A | Hypotensive | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-11-05 | — | — | US | disclosed |
| US-4880841-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |