Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 10/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10820229 | 0.90 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL12284628 | 0.90 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL9548034 | 0.87 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL51245 | 0.87 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL9548113 | 0.86 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL11218388 | 0.84 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL9548138 | 0.81 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL13067271 | 0.80 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL10820745 | 0.80 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL13623722 | 0.79 | ADRA1D (0.50) | ADRA1DADRA1AADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017803-B2 | Process for the preparation of tamsulosin and intermediates thereof | HOVIONE INTER LTD. (CH) | 2011-09-13 | — | — | US | disclosed |
| US-20090234154-A1 | Process for the preparation of tamsulosin and intermediates thereof | HOVIONE INTER LTD. | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234154-A1 | Process for the preparation of tamsulosin and intermediates thereof | AVPR2, AVPR1B, TACR2 | ADRA1D 31/4885ADRA1A 57/4885ADRA1B 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.