Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491302 | 0.74 | RARA (0.43) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL5067708 | 0.71 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAHTTCYP3A4 | |
| SCHEMBL6832471 | 0.70 | PTGS2 (0.38) | NOTUMBRD4KDM4EALDH1A1GAA | |
| SCHEMBL8380198 | 0.70 | PDE4B (0.57) | CYP1A2PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL6765715 | 0.69 | ERBB2 (0.44) | BRD4PIM1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6766113 | 0.69 | PTGS2 (0.37) | BRD4KDM4EALDH1A1GAAPOLB | |
| SCHEMBL1725632 | 0.68 | KIF11 (0.47) | NOTUM | |
| SCHEMBL5070316 | 0.68 | CHEK1 (0.51) | — | |
| SCHEMBL14484688 | 0.67 | SCN4A (0.59) | NOTUMKDM4EGAAKMT2ALMNA | |
| SCHEMBL3094563 | 0.66 | NOTUM (0.56) | NOTUMPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019759-B1 | N-ARYLTHIOLCARBAMATES, HERBICIDES CONTAINING THEM AND PROCESS FOR COMBATING UNDESIRABLE PLANT GROWTH THEREWITH | BASF Aktiengesellschaft (DE) | 1982-02-10 | — | — | EP | disclosed |