SCHEMBL1121918

SCHEMBL1121918

CCCCCCCC(=O)Oc1c[nH]c2cc(Cl)cc(Cl)c12

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 1/20 0.45
HTR2A P28223 4/20 0.44
POLM Q9NP87 2/20 0.44
POLK Q9UBT6 2/20 0.44
POLL Q9UGP5 2/20 0.44
POLH Q9Y253 2/20 0.44
HTR1A P08908 1/20 0.42
HTR1B P28222 1/20 0.42
ALOX15 P16050 4/20 0.41
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
TOP2A P11388 2/20 0.38
MAPT P10636 1/20 0.38
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5275366 0.81 ALOX15 (0.48) HTR2APOLMPOLKPOLLPOLH
SCHEMBL1122032 0.81 ALOX15 (0.48) HTR2APOLMPOLKPOLLPOLH
SCHEMBL1121921 0.81 POLM (0.41) HTR2APOLMPOLKPOLLPOLH
SCHEMBL28002128 0.78 HTR1A (0.52) HTR2AHTR1AHTR1BALOX15
SCHEMBL5073758 0.77 HTR2A (0.46) HTR2APOLMPOLKPOLLPOLH
SCHEMBL5072059 0.77 HTR2A (0.46) HTR2APOLMPOLKPOLLPOLH
SCHEMBL1122026 0.77 HTR2A (0.46) HTR2APOLMPOLKPOLLPOLH
SCHEMBL1121837 0.76 HTR1A (0.43) HTR2APOLMPOLKPOLLPOLH
SCHEMBL6142824 0.75 HTR1A (0.42) HTR2APOLMPOLKPOLLPOLH
SCHEMBL1121982 0.75 ALOX15 (0.45) POLMPOLKPOLLPOLHHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed