Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680947 | 0.83 | LMNA (0.59) | CA5ALMNAHTTNPC1GAA | |
| SCHEMBL11214407 | 0.81 | LMNA (0.51) | CA5ALMNAHTTNPC1GAA | |
| SCHEMBL11217489 | 0.80 | MEN1 (0.56) | CA5ALMNAHTTNPC1GAA | |
| SCHEMBL1031036 | 0.74 | ALDH1A1 (0.73) | LMNAGAAALDH1A1TSHRNFKB1 | |
| SCHEMBL11218208 | 0.74 | ADRB2 (0.38) | LMNAHTTNPC1MAPTSMN1; SMN2 | |
| SCHEMBL30859524 | 0.70 | LMNA (0.63) | CA5ALMNAHTTNPC1GAA | |
| SCHEMBL11187045 | 0.70 | LMNA (0.63) | CA5ALMNAHTTNPC1GAA | |
| SCHEMBL4684377 | 0.70 | PTPN11 (0.49) | HPGDALDH1A1PPARA | |
| SCHEMBL17938794 | 0.70 | CA5A (1.00) | CA5ALMNAHTTNPC1GAA | |
| SCHEMBL3527450 | 0.69 | CA5A (0.64) | CA5AGAAMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |