Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 17/20 | 0.43 |
| ▸ | MMP12 | P39900 | 17/20 | 0.43 |
| ▸ | MMP14 | P50281 | 17/20 | 0.43 |
| ▸ | MMP2 | P08253 | 16/20 | 0.43 |
| ▸ | MMP9 | P14780 | 16/20 | 0.43 |
| ▸ | MMP13 | P45452 | 15/20 | 0.43 |
| ▸ | MMP1 | P03956 | 14/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11227396 | 0.98 | MAPT (0.43) | MAPTNPC1POLBRAB9AALDH1A1 | |
| SCHEMBL13002399 | 0.97 | MAPT (0.45) | MAPTNPC1POLBRAB9AALDH1A1 | |
| SCHEMBL13002595 | 0.88 | MMP8 (0.45) | MAPTNPC1POLBRAB9AALDH1A1 | |
| SCHEMBL13002915 | 0.83 | MAPT (0.45) | MAPTNPC1POLBRAB9AALDH1A1 | |
| SCHEMBL11233273 | 0.83 | MMP9 (0.48) | MAPTNPC1POLBRAB9AALDH1A1 | |
| SCHEMBL13002430 | 0.83 | GAA (0.38) | MAPTRAB9AALDH1A1MMP8MMP12 | |
| SCHEMBL13002598 | 0.82 | CYP2A6 (0.46) | MAPTNPC1POLBRAB9AALDH1A1 | |
| SCHEMBL11385692 | 0.81 | ALDH1A1 (0.41) | MAPTNPC1POLBRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11219335 | 0.81 | MMP9 (0.47) | MAPTNPC1POLBRAB9AALDH1A1 | |
| Bromide SCHEMBL11378134 | 0.81 | MMP2 (0.47) | MAPTNPC1POLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309426-A | Muscle-relaxant 1,3,4-thiadiazin-2-amines | RICHARDSON-MERRELL INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4272532-A | SEDATIVES | RICHARDSON-MERRELL INC. (US) | 1981-06-09 | — | — | US | disclosed |