Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232203 | 0.94 | MTNR1A (0.57) | MTNR1AFFAR1MAPTGAAPOLB | |
| SCHEMBL1870686 | 0.82 | MTNR1A (0.63) | MTNR1AFFAR1MAPTGAAPOLB | |
| SCHEMBL29444764 | 0.82 | MTNR1A (0.63) | MTNR1AFFAR1MAPTGAAPOLB | |
| SCHEMBL6982719 | 0.82 | MTNR1A (0.63) | MTNR1AFFAR1MAPTGAAPOLB | |
| SCHEMBL7199006 | 0.82 | MTNR1A (0.60) | MTNR1AFFAR1MAPTGAAPOLB | |
| SCHEMBL9206095 | 0.82 | MTNR1A (0.60) | MTNR1AFFAR1MAPTGAAPOLB | |
| SCHEMBL9208736 | 0.82 | MTNR1A (0.60) | MTNR1AFFAR1MAPTGAAPOLB | |
| Hydrochloric Acid SCHEMBL7829817 | 0.81 | MTNR1A (0.58) | MTNR1AFFAR1MAPTGAAPOLB | |
| Hydrochloric Acid SCHEMBL7829814 | 0.81 | MTNR1A (0.58) | MTNR1AFFAR1MAPTGAAPOLB | |
| SCHEMBL11235851 | 0.81 | CA2 (0.56) | MTNR1AFFAR1MAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353901-A | HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIAMIGRAINE, VASOSPASTIC DISORDERS, ASTHMA | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |