Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220105 | 0.81 | MEN1 (0.52) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| Itaconic Anhydride SCHEMBL11359828 | 0.70 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10690598 | 0.65 | MEN1 (0.55) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9735914 | 0.63 | ALDH1A1 (0.44) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL657724 | 0.60 | POLB (0.53) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9541605 | 0.59 | CTRB1 (0.44) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL531416 | 0.58 | TSHR (0.56) | HTR2AHTR2CHTR2B | |
| SCHEMBL1583198 | 0.58 | TSHR (0.56) | HTR2AHTR2CHTR2B | |
| SCHEMBL1022637 | 0.58 | TSHR (0.56) | HTR2AHTR2CHTR2B | |
| SCHEMBL20177951 | 0.58 | HTR3A (0.47) | KMT2AKDM4EALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | claimed |
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4308381-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4245088-A | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |