Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069761 | 0.85 | HSD11B1 (0.38) | HSD11B1SIGMAR1DRD2HTR2A | |
| SCHEMBL27286586 | 0.81 | HSD11B1 (0.48) | HSD11B1 | |
| SCHEMBL9113086 | 0.78 | SIGMAR1 (0.46) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| SCHEMBL546544 | 0.77 | SIGMAR1 (0.45) | SIGMAR1DRD2HTR2ATRPM8ALDH1A1 | |
| SCHEMBL29736073 | 0.77 | SIGMAR1 (0.45) | SIGMAR1DRD2HTR2ATRPM8ALDH1A1 | |
| SCHEMBL27286587 | 0.77 | ALDH1A1 (0.38) | HSD11B1SIGMAR1DRD2HTR2ATRPM8 | |
| SCHEMBL11274144 | 0.76 | SIGMAR1 (0.42) | SIGMAR1DRD2HTR2ATRPM8ADRA1D | |
| Methyl Alcohol SCHEMBL28796336 | 0.76 | SIGMAR1 (0.42) | SIGMAR1DRD2HTR2ATRPM8ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL29163352 | 0.76 | SIGMAR1 (0.44) | SIGMAR1DRD2HTR2ATRPM8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27471847 | 0.76 | SIGMAR1 (0.44) | SIGMAR1DRD2HTR2ATRPM8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117990822-A | Method for determining content of 6 components in traditional Chinese medicine composition containing rehmannia root based on LC-MS and application | 上海黄海制药有限责任公司 | 2024-05-07 | — | — | CN | claimed |
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | claimed |
| CN-117990822-A | Method for determining content of 6 components in traditional Chinese medicine composition containing rehmannia root based on LC-MS and application | 上海黄海制药有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-0051061-A2 | Novel intermediates and process for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-05-05 | — | — | EP | disclosed |