Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | GCG | P01275 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220472 | 0.88 | NPSR1 (0.47) | NPSR1RAB9AITGB3ITGAVKMT2A | |
| SCHEMBL11318864 | 0.87 | KMT2A (0.43) | NPSR1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL11220562 | 0.84 | HTT (0.44) | NPSR1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11310145 | 0.84 | NPSR1 (0.45) | NPSR1TSHRRAB9AKMT2AMEN1 | |
| SCHEMBL11314723 | 0.82 | SMN1; SMN2 (0.43) | NPSR1TSHRKMT2AMEN1POLB | |
| SCHEMBL11310121 | 0.80 | HTT (0.44) | NPSR1RAB9AKMT2AMEN1POLB | |
| SCHEMBL11311686 | 0.79 | PTGIR (0.41) | NPSR1RAB9APOLBALDH1A1KDM4E | |
| SCHEMBL11325054 | 0.79 | NPSR1 (0.39) | NPSR1RAB9AKMT2AMEN1POLB | |
| SCHEMBL11223592 | 0.77 | RAB9A (0.49) | NPSR1TSHRRAB9AKMT2AMEN1 | |
| SCHEMBL11314690 | 0.77 | HDAC6 (0.39) | NPSR1RAB9AITGB3ITGAVPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003056-B1 | N-SUBSTITUTED OMEGA-AMINOALKANOYL-OMEGA-AMINOALKANECARBOXYLIC ACIDS, THEIR APPLICATION AND PROCESS FOR THEIR PREPARATION, AND MEDICINES CONTAINING THESE COMPOUNDS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |