Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212933 | 0.80 | HPGD (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1SIGMAR1 | |
| SCHEMBL11210225 | 0.73 | NPC1 (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL12497620 | 0.68 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2ATSHRMEN1 | |
| SCHEMBL18194345 | 0.66 | ALDH1A1 (0.37) | ALDH1A1SIGMAR1MAOAMAOB | |
| Biphenyl SCHEMBL473288 | 0.65 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL1 | |
| Biphenyl SCHEMBL335359 | 0.65 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL1 | |
| Biphenyl SCHEMBL4593266 | 0.65 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL1 | |
| Biphenyl SCHEMBL1952613 | 0.65 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL1 | |
| SCHEMBL9234149 | 0.64 | PGR (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL28696957 | 0.64 | CYP11B2 (0.39) | ALDH1A1SMN1; SMN2LMNAHPGDBCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022087-B1 | STABILIZERS FOR THERMOPLASTS THAT CONTAIN CHLORINE | CIBA-GEIGY AG (CH) | 1983-11-23 | — | — | EP | claimed |