SCHEMBL11220747

SCHEMBL11220747

O=C(O)CCCC(CC(=O)O)P(=O)(O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 8/20 0.53
NAALAD2 Q9Y3Q0 1/20 0.42
LMNA P02545 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
ENPEP Q07075 2/20 0.39
GSTK1 Q9Y2Q3 2/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
GRM3 Q14832 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10699967 0.92 LMNA (0.46) FOLH1NAALAD2LMNAENPEPGSTK1
SCHEMBL8632600 0.87 FOLH1 (0.54) FOLH1NAALAD2LMNATSHRGRM3
SCHEMBL8013616 0.85 FOLH1 (0.52) FOLH1NAALAD2LMNATSHRGRM3
SCHEMBL9461885 0.79 FOLH1 (0.52) FOLH1NAALAD2LMNASLC22A6TSHR
SCHEMBL9486364 0.79 GPR84 (0.56)
SCHEMBL15068281 0.79 GPR84 (0.56)
SCHEMBL9485772 0.79 GPR84 (0.56)
SCHEMBL11227702 0.78 FOLH1 (0.43) FOLH1NAALAD2LMNASLC22A6TSHR
SCHEMBL8718703 0.77 FDPS (0.48) FOLH1
SCHEMBL28018475 0.76 FOLH1 (0.46) FOLH1NAALAD2ENPEPGSTK1GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4320025-A Cavitation-inhibiting, nonfreezing, cooling and/or heat transfer fluids CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DE) 1982-03-16 US disclosed