Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461885 | 0.83 | FOLH1 (0.52) | FOLH1TDP1MEN1LMNAHPGD | |
| SCHEMBL8632600 | 0.82 | FOLH1 (0.54) | FOLH1TDP1MEN1LMNAHPGD | |
| SCHEMBL8013616 | 0.80 | FOLH1 (0.52) | FOLH1TDP1MEN1LMNAHPGD | |
| SCHEMBL8718703 | 0.80 | FDPS (0.48) | FOLH1TDP1 | |
| SCHEMBL11220747 | 0.78 | FOLH1 (0.53) | FOLH1LMNATSHRNAALAD2SLC22A6 | |
| SCHEMBL10877254 | 0.75 | LMNA (0.34) | FOLH1LMNASLC22A6 | |
| SCHEMBL10699967 | 0.75 | LMNA (0.46) | FOLH1LMNATSHRNAALAD2 | |
| SCHEMBL8781578 | 0.74 | FOLH1 (0.45) | FOLH1TDP1MEN1LMNAHPGD | |
| SCHEMBL7623237 | 0.74 | GAA (0.42) | MEN1TSHRKMT2ACA2CA4 | |
| SCHEMBL9485772 | 0.74 | GPR84 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358587-A | Water-soluble cellulose mixed ethers which contain a phosphonomethyl substituent and a process for preparing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |