Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Diethoxybenzene SCHEMBL1100167 | 0.72 | TP53 (0.71) | TP53CYP3A4MAPTSMN1; SMN2MEN1 | |
| Phenetole SCHEMBL18492 | 0.70 | — | — | |
| Phenetole SCHEMBL10779391 | 0.70 | LTA4H (0.81) | TP53CYP3A4SMN1; SMN2LTA4HMAPK1 | |
| Phenetole SCHEMBL499918 | 0.70 | LTA4H (0.81) | TP53CYP3A4SMN1; SMN2LTA4HMAPK1 | |
| SCHEMBL30338775 | 0.70 | RXRA (0.70) | TP53CYP3A4MAPTSMN1; SMN2NOTUM | |
| SCHEMBL5986733 | 0.70 | LTA4H (0.73) | TP53CYP3A4SMN1; SMN2LTA4HMAPK1 | |
| SCHEMBL203120 | 0.70 | RXRA (0.70) | TP53CYP3A4MAPTSMN1; SMN2NOTUM | |
| SCHEMBL444779 | 0.69 | SMN1; SMN2 (0.49) | TP53CYP3A4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9506055 | 0.68 | MEN1 (0.58) | TP53CYP3A4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6922833 | 0.68 | ADRB1 (0.69) | TP53CYP3A4MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080053-A1 | 3,5-Diphenyl-1H-1,2,4-triazoles with contragestational activity, pharmaceutical compositions thereof and process for their preparation | GRUPPO LEPETIT S.P.A. (IT) | 1983-06-01 | — | — | EP | disclosed |