Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223677 | 0.88 | EGFR (0.34) | KMT2AMEN1MLYCD | |
| SCHEMBL11229091 | 0.82 | LMNA (0.34) | KMT2AMEN1LMNAMLYCD | |
| SCHEMBL11227132 | 0.82 | RXRA (0.40) | KMT2AMEN1MLYCD | |
| SCHEMBL11223682 | 0.82 | KMT2A (0.35) | KMT2AMEN1LMNAMLYCD | |
| SCHEMBL11229519 | 0.82 | SMN1; SMN2 (0.44) | KMT2AMEN1LMNA | |
| SCHEMBL11236806 | 0.80 | FOLH1 (0.33) | KMT2AMEN1LMNAMLYCD | |
| SCHEMBL11228750 | 0.80 | FOLH1 (0.40) | KMT2AMEN1LMNAMLYCD | |
| SCHEMBL11230871 | 0.80 | CYP4F2 (0.39) | KMT2AMEN1LMNA | |
| SCHEMBL11232678 | 0.79 | MLYCD (0.37) | KMT2ALMNAMLYCD | |
| SCHEMBL11223288 | 0.77 | MEN1 (0.37) | KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361579-A | TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0025965-A2 | Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |