Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 2/20 | 0.32 |
| ▸ | PPIB | P23284 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227132 | 0.82 | RXRA (0.40) | KMT2AMEN1POLQMLYCD | |
| SCHEMBL11223677 | 0.82 | EGFR (0.34) | KMT2AMEN1POLQPPIBMLYCD | |
| SCHEMBL11229091 | 0.82 | LMNA (0.34) | KMT2AMEN1POLQPPIBMLYCD | |
| SCHEMBL11221077 | 0.82 | MCHR1 (0.38) | KMT2AMEN1MLYCDLMNA | |
| SCHEMBL11239919 | 0.81 | SMN1; SMN2 (0.44) | KMT2ANOTUMLMNAPOLBSMN1; SMN2 | |
| SCHEMBL11236806 | 0.80 | FOLH1 (0.33) | KMT2AMEN1MLYCDLMNAPOLB | |
| SCHEMBL11228750 | 0.80 | FOLH1 (0.40) | KMT2AMEN1POLQMLYCDLMNA | |
| SCHEMBL11223288 | 0.80 | MEN1 (0.37) | KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL21765667 | 0.80 | KMT2A (0.46) | KMT2AMEN1NOTUMPOLQMLYCD | |
| SCHEMBL11229519 | 0.79 | SMN1; SMN2 (0.44) | KMT2AMEN1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361579-A | TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0025965-A2 | Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |