Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 10/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229913 | 0.88 | NAAA (0.57) | NAAACTSLCTSBCTSKDRD4 | |
| SCHEMBL22788778 | 0.86 | NAAA (0.42) | NAAACTSLCTSBCTSKDRD4 | |
| SCHEMBL11232037 | 0.86 | CARM1 (0.52) | NAAACTSLCTSBCTSKDRD4 | |
| SCHEMBL11229024 | 0.86 | CTSL (0.58) | NAAACTSLCTSBCTSKTMEM97 | |
| SCHEMBL11236001 | 0.85 | NAAA (0.59) | NAAASIGMAR1 | |
| SCHEMBL11226439 | 0.84 | NAAA (0.45) | NAAACTSLCTSBCTSKTMEM97 | |
| SCHEMBL11230944 | 0.83 | NAAA (0.45) | NAAACTSLCTSBCTSKDRD4 | |
| SCHEMBL26241235 | 0.83 | CARM1 (0.42) | NAAACTSLCTSBCTSKDRD4 | |
| SCHEMBL11231901 | 0.81 | NAAA (0.43) | NAAACTSLCTSBCTSKCARM1 | |
| SCHEMBL18615720 | 0.76 | CARM1 (0.43) | DRD4TMEM97SIGMAR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | claimed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |