Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 8/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221135 | 0.88 | NAAA (0.44) | NAAASIGMAR1DRD4TMEM97CTSL | |
| SCHEMBL22788778 | 0.85 | NAAA (0.42) | NAAASIGMAR1DRD4TMEM97CTSL | |
| SCHEMBL11232037 | 0.85 | CARM1 (0.52) | NAAASIGMAR1DRD4TMEM97CTSL | |
| SCHEMBL11229024 | 0.84 | CTSL (0.58) | NAAASIGMAR1TMEM97ALDH1A1CTSL | |
| SCHEMBL11236001 | 0.83 | NAAA (0.59) | NAAASIGMAR1AGXTHRH3 | |
| SCHEMBL11222724 | 0.82 | NAAA (0.60) | NAAASIGMAR1DRD4TMEM97CTSL | |
| SCHEMBL11230944 | 0.82 | NAAA (0.45) | NAAASIGMAR1DRD4TMEM97ALDH1A1 | |
| SCHEMBL11232973 | 0.78 | NAAA (0.56) | NAAASIGMAR1DRD4TMEM97CTSL | |
| SCHEMBL11236472 | 0.78 | NAAA (0.56) | NAAASIGMAR1DRD4TMEM97CTSL | |
| SCHEMBL8930166 | 0.77 | NAAA (0.54) | NAAASIGMAR1DRD4TMEM97AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | claimed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |