Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 8/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24213030 | 0.87 | CARM1 (0.59) | CTSLCTSBCTSKCARM1PRMT6 | |
| SCHEMBL11232221 | 0.86 | CTSL (0.55) | CTSLCTSBCTSKCARM1PRMT6 | |
| SCHEMBL11221135 | 0.86 | NAAA (0.44) | CTSLCTSBCTSKCARM1PRMT6 | |
| SCHEMBL11229913 | 0.84 | NAAA (0.57) | CTSLCTSBCTSKTMEM97SIGMAR1 | |
| SCHEMBL11226960 | 0.84 | CTSL (0.60) | CTSLCTSBCTSKCARM1PRMT6 | |
| SCHEMBL11232037 | 0.83 | CARM1 (0.52) | CTSLCTSBCTSKCARM1PRMT6 | |
| SCHEMBL22788778 | 0.83 | NAAA (0.42) | CTSLCTSBCTSKCARM1PRMT6 | |
| SCHEMBL23972324 | 0.83 | CARM1 (0.67) | CTSLCTSBCTSKCARM1PRMT6 | |
| SCHEMBL9965812 | 0.81 | CTSL (0.62) | CTSLCTSBCTSKCARM1PRMT6 | |
| SCHEMBL21652008 | 0.81 | CTSL (0.54) | CTSLCTSBCTSKCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | claimed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |