Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CDC42 | P60953 | 1/20 | 0.62 |
| ▸ | RAC1 | P63000 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10406806 | 1.00 | TDP1 (0.74) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL10407187 | 0.89 | TDP1 (0.71) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL10407191 | 0.88 | TDP1 (0.72) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL10407192 | 0.87 | TDP1 (0.67) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL9284416 | 0.85 | TDP1 (1.00) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL506523 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL31619540 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL3280876 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL221436 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 | |
| SCHEMBL9717784 | 0.83 | TDP1 (0.78) | TDP1L3MBTL1AKR1C3AKR1C2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709847-A | TOPICAL APPLICATION TO PREVENT DAMAGE TO SKIN BY ACCUTE ORCHRONIC UV EXPOSURE | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-20 | — | — | US | claimed |
| US-5384115-A | Photoprotection compositions comprising a radical scavenging compound and an anti-inflammatory agent | THE PROCTER & GAMBLE COMPANY (US) | 1995-01-24 | — | — | US | claimed |
| US-4912248-A | A 2-naphthyl containing ester | THE PROCTER & GAMBLE COMPANY (US) | 1990-03-27 | — | — | US | claimed |
| US-20170173004-A1 | Methods For Treating Inflammatory Conditions | CAVALRY FUND I LP | 2017-06-22 | — | — | US | disclosed |
| US-9408844-B2 | Methods for treating inflammatory conditions | MELIOR DISCOVERY, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| CN-104219952-A | Skin lightening compositions | LASYA INC | 2014-12-17 | — | — | CN | disclosed |
| EP-2800470-A1 | SKIN LIGHTENING COMPOSITIONS | Merz North America, Inc. (US) | 2014-11-12 | — | — | EP | disclosed |
| US-20140227209-A1 | Methods For Treating Inflammatory Conditions | MELIOR DISCOVERY, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8716294-B2 | Methods for treating inflammatory conditions | MELIOR DISCOVERY, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20130224137-A1 | SKIN LIGHTENING COMPOSITIONS | LASYA, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| WO-2013103874-A1 | SKIN LIGHTENING COMPOSITIONS | LASYA, INC. (US) | 2013-07-11 | — | — | WO | disclosed |
| US-4869897-A | SUNCREEN AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| US-4847069-A | SUNSCREEN AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4847072-A | SUNSCREEN AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4847071-A | SUNSCREEN AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0313305-A2 | Photoprotection compositions comprising chelating agents | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313303-A2 | Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313347-A2 | Photoprotection compositions comprising sorbohydroxamic acid and an anti-inflammatory agent | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313302-A2 | Photoprotection compositions comprising sorbohydroxamic acid | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313304-A2 | Photoprotection compositions comprising tocopherol sorbate | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173004-A1 | Methods For Treating Inflammatory Conditions | TSLP, TLR3, TLR4 | TDP1 3039/4885L3MBTL1 2312/4885AKR1C3 1830/4885 |
| US-20130224137-A1 | SKIN LIGHTENING COMPOSITIONS | CUTA, COL14A1, COLGALT1 | TDP1 1929/4885L3MBTL1 1310/4885AKR1C3 2623/4885 |
| US-20140227209-A1 | Methods For Treating Inflammatory Conditions | TSLP, TLR3, TLR4 | TDP1 3039/4885L3MBTL1 2312/4885AKR1C3 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.