Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221559 | 1.00 | PTGS2 (0.50) | PTGS2ALDH1A1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL11404916 | 0.81 | LMNA (0.50) | PTGS2ALDH1A1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL11404055 | 0.80 | PTGS2 (0.53) | PTGS2ALDH1A1SMN1; SMN2TSHRHPGD | |
| SCHEMBL11409272 | 0.78 | PBRM1 (0.49) | PTGS2ALDH1A1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL11409270 | 0.78 | PBRM1 (0.49) | PTGS2ALDH1A1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL11416851 | 0.77 | DHODH (0.44) | PTGS2ALDH1A1TSHRHPGDKDM4E | |
| SCHEMBL11416848 | 0.77 | DHODH (0.44) | PTGS2ALDH1A1TSHRHPGDKDM4E | |
| SCHEMBL11402270 | 0.77 | ALDH1A1 (0.52) | PTGS2ALDH1A1SMN1; SMN2TSHRHPGD | |
| SCHEMBL11405776 | 0.77 | TSHR (0.53) | PTGS2ALDH1A1SMN1; SMN2TSHRHPGD | |
| SCHEMBL11408187 | 0.77 | PTGS2 (0.50) | PTGS2ALDH1A1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57050952-A | — | — | None | — | — | JP | disclosed |
| JP-55145652-A | — | — | None | — | — | JP | disclosed |
| JP-S5750952-A | BENZOIC ACID DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1982-03-25 | — | — | JP | disclosed |
| JP-S55145652-A | BENZOIC ACID DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1980-11-13 | — | — | JP | disclosed |