Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.49 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689889 | 1.00 | HPGD (0.50) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL11221674 | 0.95 | MAPT (0.47) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL11225617 | 0.89 | TRPM4 (0.48) | HPGDNCEH1TRPM4KDM4EALDH1A1 | |
| SCHEMBL11024895 | 0.88 | NCEH1 (0.45) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL6545326 | 0.88 | HPGD (0.47) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL7915017 | 0.83 | HTR2A (0.52) | HPGDNPC1NCEH1KDM4EALDH1A1 | |
| SCHEMBL10933274 | 0.83 | ALOX5 (0.49) | HPGDTRPM4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8517831 | 0.83 | HPGD (0.43) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL21569596 | 0.82 | NCEH1 (0.46) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL28860671 | 0.82 | SLC37A4 (0.51) | HPGDNCEH1KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117209343-A | Continuous synthesis method of 2-naphthol compound | 菏泽学院 | 2023-12-12 | — | — | CN | disclosed |
| EP-0068398-B1 | THERMOPLASTIC MOULDING COMPOSITIONS BASED ON VINYL CHLORIDE POLYMERS AND IMPACT MODIFYING POLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-08 | — | — | EP | disclosed |
| EP-0043965-B1 | PROCESS FOR PRODUCING STAMPINGS HAVING AN INCREASED WHITE FRACTURE EFFECT IN SHEETS OF VINYL CHLORIDE POLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-12 | — | — | EP | disclosed |
| US-4463119-A | CONTAINING SOLID OR LIQUID POLYSILOXANES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-31 | — | — | US | disclosed |
| EP-0104433-A1 | Moulded mass for extruding hollow bodies and profiles with an opaque surface | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-04-04 | — | — | EP | disclosed |
| EP-0068398-A1 | Thermoplastic moulding compositions based on vinyl chloride polymers and impact modifying polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |
| US-4323714-A | Alkylation of hydroxy-substituted aromatic compounds | UOP INC. (US) | 1982-04-06 | — | — | US | disclosed |
| EP-0043965-A1 | Process for producing stampings having an increased white fracture effect in sheets of vinyl chloride polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-20 | — | — | EP | disclosed |
| US-4113679-A | Antistatic thermoplastic molding compositions and shaped articles made therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4082711-A | COELASTOMER, PLASTICIZING | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |