Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976271 | 0.88 | HPGD (0.50) | NCEH1HPGDNPC1MAPK1HTT | |
| SCHEMBL30689889 | 0.88 | HPGD (0.50) | NCEH1HPGDNPC1MAPK1HTT | |
| SCHEMBL6545326 | 0.87 | HPGD (0.47) | NCEH1HPGDNPC1MAPK1HTT | |
| SCHEMBL8517831 | 0.84 | HPGD (0.43) | NCEH1HPGDNPC1MAPK1HTT | |
| SCHEMBL11221674 | 0.83 | MAPT (0.47) | NCEH1HPGDNPC1MAPK1HTT | |
| SCHEMBL2126066 | 0.83 | NCEH1 (0.43) | NCEH1HPGDRAB9AKDM4EALDH1A1 | |
| SCHEMBL7915017 | 0.82 | HTR2A (0.52) | NCEH1HPGDNPC1KDM4EALDH1A1 | |
| SCHEMBL10933274 | 0.82 | ALOX5 (0.49) | HPGDTRPM4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL21569596 | 0.80 | NCEH1 (0.46) | NCEH1HPGDNPC1MAPK1HTT | |
| SCHEMBL28860671 | 0.80 | SLC37A4 (0.51) | NCEH1HPGDKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083428-B1 | PROCESS FOR PRODUCING BETA-NAPHTHOLS NOT SUBSTITUTED IN POSITION 1 AND SUBSTITUTED BY ARALIPHATIC GROUPS | BASF Aktiengesellschaft (DE) | 1985-07-10 | — | — | EP | disclosed |
| EP-0083428-A1 | Process for producing beta-naphthols not substituted in position 1 and substituted by araliphatic groups | BASF Aktiengesellschaft (DE) | 1983-07-13 | — | — | EP | disclosed |