Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221785 | 0.84 | SMN1; SMN2 (0.46) | GAAHPGDSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11276287 | 0.83 | HPGD (0.51) | GAAHPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL11275087 | 0.83 | HPGD (0.46) | GAAHPGDSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL55223 | 0.83 | HPGD (0.46) | GAAHPGDSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11280415 | 0.81 | RIPK1 (0.39) | ACHEGAAGRM5CYP2C9CYP2C19 | |
| SCHEMBL9292283 | 0.81 | SIGMAR1 (0.49) | HPGDSMN1; SMN2ALDH1A1HSD17B10CHRM3 | |
| SCHEMBL11278852 | 0.76 | HPGD (0.49) | GAAHPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| Endothall SCHEMBL4963604 | 0.76 | TFPI2 (0.47) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6647193 | 0.75 | ACHE (0.54) | ACHEGAAGRM5CYP2C9CYP2C19 | |
| SCHEMBL20618549 | 0.73 | ACHE (0.55) | ACHEGAAGRM5HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343737-A | Process for production of thiolcarbamates and the thiolcarbamates obtained by said process | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1982-08-10 | — | — | US | disclosed |
| US-4298740-A | REACTION OF TERTIARY HALOGEN COMPOUND WITH THIOLCARBAMIC ACID SALT | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |