SCHEMBL1122189

SCHEMBL1122189

CCCCCCCC(=O)Oc1c(Cl)c2ccccc2n1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
POLM Q9NP87 1/20 0.42
POLK Q9UBT6 1/20 0.42
POLL Q9UGP5 1/20 0.42
POLH Q9Y253 1/20 0.42
HTR7 P34969 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PSEN1 P49768 1/20 0.39
PSEN2 P49810 1/20 0.39
APH1B Q8WW43 1/20 0.39
NCSTN Q92542 1/20 0.39
APH1A Q96BI3 1/20 0.39
PSENEN Q9NZ42 1/20 0.39
ICMT O60725 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
HPSE Q9Y251 1/20 0.39
PLA2G2A P14555 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122197 0.86 HTR7 (0.39) POLMPOLKPOLLPOLHHTR7
SCHEMBL1122592 0.83 POLM (0.40) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15558926 0.76 KMT2A (0.46) POLMPOLKPOLLPOLHHTR7
SCHEMBL1121909 0.74 OXER1 (0.44) POLMPOLKPOLLPOLHKMT2A
SCHEMBL23271733 0.73 EPHX2 (0.51) POLMPOLKPOLLPOLHKMT2A
SCHEMBL29370938 0.73 EPHX2 (0.51) POLMPOLKPOLLPOLHKMT2A
SCHEMBL29368355 0.73 EPHX2 (0.51) POLMPOLKPOLLPOLHKMT2A
SCHEMBL20398671 0.73 EPHX2 (0.51) POLMPOLKPOLLPOLHKMT2A
SCHEMBL20398624 0.73 EPHX2 (0.51) POLMPOLKPOLLPOLHKMT2A
SCHEMBL29371710 0.73 EPHX2 (0.51) POLMPOLKPOLLPOLHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed