SCHEMBL1122197

SCHEMBL1122197

CCCCCCCC(=O)Oc1c(Br)c2ccccc2n1Cl

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 2/20 0.39
KMT2A Q03164 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PSEN1 P49768 1/20 0.39
PSEN2 P49810 1/20 0.39
APH1B Q8WW43 1/20 0.39
NCSTN Q92542 1/20 0.39
APH1A Q96BI3 1/20 0.39
PSENEN Q9NZ42 1/20 0.39
ICMT O60725 1/20 0.39
POLM Q9NP87 1/20 0.39
POLK Q9UBT6 1/20 0.39
POLL Q9UGP5 1/20 0.39
POLH Q9Y253 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
HPSE Q9Y251 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122189 0.86 L3MBTL1 (0.43) HTR7KMT2ASMN1; SMN2PSEN1PSEN2
SCHEMBL15558926 0.75 KMT2A (0.46) HTR7KMT2ASMN1; SMN2PSEN1PSEN2
SCHEMBL1122592 0.75 POLM (0.40) KMT2ASMN1; SMN2POLMPOLKPOLL
SCHEMBL1121909 0.73 OXER1 (0.44) KMT2ASMN1; SMN2POLMPOLKPOLL
SCHEMBL23271733 0.72 EPHX2 (0.51) KMT2ASMN1; SMN2POLMPOLKPOLL
SCHEMBL29368355 0.72 EPHX2 (0.51) KMT2ASMN1; SMN2POLMPOLKPOLL
SCHEMBL29370938 0.72 EPHX2 (0.51) KMT2ASMN1; SMN2POLMPOLKPOLL
SCHEMBL20398671 0.72 EPHX2 (0.51) KMT2ASMN1; SMN2POLMPOLKPOLL
SCHEMBL20398624 0.72 EPHX2 (0.51) KMT2ASMN1; SMN2POLMPOLKPOLL
SCHEMBL29360726 0.72 EPHX2 (0.51) KMT2ASMN1; SMN2POLMPOLKPOLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed