Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.55 |
| ▸ | PDE4A | P27815 | 4/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420242 | 0.95 | THRA (0.60) | HTTLMNAMAPK1RAB9ATHRA | |
| SCHEMBL5729116 | 0.91 | RAB9A (0.63) | HTTLMNAMAPK1RAB9ATHRA | |
| SCHEMBL29670763 | 0.86 | CTNNB1 (0.67) | THRATHRBPDE4DPDE4APDE4B | |
| SCHEMBL4861157 | 0.86 | CTNNB1 (0.67) | THRATHRBPDE4DPDE4APDE4B | |
| SCHEMBL7389336 | 0.85 | HTT (0.56) | HTTLMNAMAPK1RAB9ATHRA | |
| SCHEMBL6580881 | 0.84 | HTT (0.63) | HTTLMNAMAPK1RAB9ATHRA | |
| SCHEMBL8984320 | 0.84 | THRA (0.60) | THRATHRBHRH3 | |
| SCHEMBL8035601 | 0.84 | HTT (0.55) | HTTLMNAMAPK1RAB9ATHRA | |
| SCHEMBL2845183 | 0.84 | HTT (0.67) | HTTLMNAMAPK1RAB9ATAS1R3 | |
| SCHEMBL10454879 | 0.84 | MGLL (0.57) | HTTLMNAMAPK1RAB9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366330-A | A FLUOROPHENOL CAPABLE OF BEING REACTED WITH AN ARYL OR CYCLOALKYL CARBOXYLIC ACID TO PRODUCT AN ESTER | BCH CHEMICALS LIMITED (GB) | 1982-12-28 | — | — | US | disclosed |