Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.39 |
| ▸ | TUBB | P07437 | 3/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223661 | 0.82 | MAPT (0.46) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL7695295 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TDP1MAPTLMNAHSP90AA1 | |
| SCHEMBL1639302 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL17035156 | 0.74 | TDP1 (0.53) | ALDH1A1TDP1MAPTLMNAS100A4 | |
| SCHEMBL28124084 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPTLMNAHSP90AA1 | |
| SCHEMBL6936039 | 0.74 | TDP1 (0.43) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL11222808 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL28337676 | 0.73 | HSD17B10 (0.35) | ALDH1A1MAPTMEN1KMT2ACA1 | |
| SCHEMBL1287837 | 0.73 | ALDH1A1 (0.74) | ALDH1A1TDP1S100A4PTPRCGPR35 | |
| SCHEMBL30535903 | 0.73 | ALDH1A1 (0.74) | ALDH1A1TDP1S100A4PTPRCGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363905-A | PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4316981-A | Polycarbonate transesterification | GENERAL ELECTRIC COMPANY (US) | 1982-02-23 | — | — | US | disclosed |