Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 5/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223683 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1NFKB1SMN1; SMN2EIF4E | |
| SCHEMBL16919513 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TDP1NPC1RAB9AMAPT | |
| SCHEMBL1639302 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1NPC1RAB9AMAPT | |
| SCHEMBL8061304 | 0.76 | CASP6 (0.41) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11222802 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TDP1NPC1RAB9AMAPT | |
| SCHEMBL6309234 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29911025 | 0.72 | ALDH1A1 (0.60) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL57736 | 0.72 | ALDH1A1 (0.60) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15055251 | 0.71 | ALDH1A1 (0.66) | ALDH1A1TDP1NPC1RAB9AMAPT | |
| SCHEMBL483903 | 0.71 | ALDH1A1 (0.71) | ALDH1A1TDP1NPC1RAB9AEIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363905-A | PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4316981-A | Polycarbonate transesterification | GENERAL ELECTRIC COMPANY (US) | 1982-02-23 | — | — | US | disclosed |