Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222802 | 0.82 | ALDH1A1 (0.44) | MAPTALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL4583256 | 0.77 | ALDH1A1 (0.59) | MAPTPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1639302 | 0.76 | ALDH1A1 (0.50) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL29236126 | 0.74 | MAPT (0.52) | MAPTPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11647517 | 0.73 | MAPT (0.55) | MAPTPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11223683 | 0.73 | ALDH1A1 (0.47) | MAPTPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8065623 | 0.73 | KMT2A (0.52) | POLBALDH1A1HPGDTDP1PTPN7 | |
| SCHEMBL1287837 | 0.73 | ALDH1A1 (0.74) | ALDH1A1HPGDNPC1CYP3A4CYP2D6 | |
| SCHEMBL30535903 | 0.73 | ALDH1A1 (0.74) | ALDH1A1HPGDNPC1CYP3A4CYP2D6 | |
| SCHEMBL11223718 | 0.72 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363905-A | PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4316981-A | Polycarbonate transesterification | GENERAL ELECTRIC COMPANY (US) | 1982-02-23 | — | — | US | disclosed |