Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | EIF4E | P06730 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222808 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1EIF4ELMNAMAPT | |
| SCHEMBL29962438 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1EIF4EHPGDGSK3A | |
| SCHEMBL1558204 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1EIF4EHPGDGSK3A | |
| SCHEMBL1639302 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1HPGDLMNAMAPT | |
| SCHEMBL8061304 | 0.76 | CASP6 (0.41) | ALDH1A1TDP1MAPTMEN1CYP1A2 | |
| SCHEMBL11223661 | 0.73 | MAPT (0.46) | ALDH1A1TDP1EIF4EHPGDLMNA | |
| SCHEMBL28193616 | 0.73 | HSD17B10 (0.61) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL23166790 | 0.73 | TDP1 (0.54) | ALDH1A1TDP1EIF4EHPGDPTGS2 | |
| SCHEMBL6309234 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TDP1HPGDMAPTGAA | |
| SCHEMBL29911025 | 0.72 | ALDH1A1 (0.60) | ALDH1A1TDP1HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363905-A | PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4316981-A | Polycarbonate transesterification | GENERAL ELECTRIC COMPANY (US) | 1982-02-23 | — | — | US | disclosed |