Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017479 | 0.88 | FOLH1 (0.39) | NAALAD2ALDH1A1MEN1KMT2AESR1 | |
| SCHEMBL3382753 | 0.85 | NAALAD2 (0.42) | NAALAD2ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL3380551 | 0.82 | ALDH1A1 (0.41) | NAALAD2ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8585562 | 0.82 | NAALAD2 (0.40) | NAALAD2ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8460189 | 0.80 | ALDH1A1 (0.40) | NAALAD2ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL12931443 | 0.80 | FDPS (0.48) | FDPS | |
| SCHEMBL3380370 | 0.79 | ALDH1A1 (0.39) | NAALAD2ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11489691 | 0.78 | GRM4 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL871609 | 0.77 | TSHR (0.48) | ALDH1A1MEN1KMT2ATSHRHIF1A | |
| SCHEMBL11296652 | 0.77 | FDPS (0.50) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346225-A2 | METHOD FOR IDENTIFYING SUBSTANCES WHICH POSITIVELY INFLUENCE INFLAMMATORY CONDITIONS OF CHRONIC INFLAMMATORY AIRWAY DISEASES | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-09-24 | — | — | EP | disclosed |
| US-20020137099-A1 | Methods for identifying substances for treating inflammatory conditions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-09-26 | — | — | US | disclosed |
| WO-2002052269-A2 | METHOD FOR IDENTIFYING SUBSTANCES WHICH POSITIVELY INFLUENCE INFLAMMATORY CONDITIONS OF CHRONIC INFLAMMATORY AIRWAY DISEASES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |
| US-5273549-A | Crosslinking agent containing at least two carboxyl groups and a phosphate group | SOCIETE FRANCAISE HOECHST (FR) | 1993-12-28 | — | — | US | disclosed |