Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.65 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | CCR3 | P51677 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | CTSC | P53634 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379927 | 0.86 | MCHR1 (0.69) | MCHR1SLC6A12TMEM97SIGMAR1CCR3 | |
| SCHEMBL11103818 | 0.86 | CARM1 (0.73) | MCHR1SLC6A12TMEM97SIGMAR1CCR3 | |
| SCHEMBL6378472 | 0.84 | MCHR1 (0.66) | MCHR1SLC6A12TMEM97SIGMAR1CCR3 | |
| SCHEMBL21652025 | 0.83 | MCHR1 (0.68) | MCHR1SLC6A12TMEM97SIGMAR1CCR3 | |
| SCHEMBL11359493 | 0.82 | ALDH1A1 (0.62) | TMEM97SIGMAR1DRD4CARM1PRMT6 | |
| SCHEMBL4749226 | 0.81 | NPC1 (0.67) | MCHR1SLC6A12TMEM97SIGMAR1CCR3 | |
| SCHEMBL11832174 | 0.80 | MCHR1 (0.64) | MCHR1SLC6A12TMEM97SIGMAR1CCR3 | |
| SCHEMBL11626419 | 0.79 | ADRA1A (0.86) | MCHR1SLC6A12TMEM97SIGMAR1CCR3 | |
| SCHEMBL1425074 | 0.79 | SIGMAR1 (1.00) | MCHR1SLC6A12TMEM97SIGMAR1CCR3 | |
| SCHEMBL10928970 | 0.79 | HTR2A (0.72) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330549-A | Coumarins connected via an oxyalkyl group with a piperidine ring having anti-allergic action | BOEHRINGER MANNHEIM GMBH (DE) | 1982-05-18 | — | — | US | disclosed |