Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378390 | 0.84 | PTGS1 (0.56) | KEAP1L3MBTL1NFE2L2PTGS1PTGS2 | |
| SCHEMBL4860020 | 0.82 | PTGS1 (0.63) | L3MBTL1PTGS1KMT2ASLC22A12KDM4E | |
| SCHEMBL1797703 | 0.79 | KEAP1 (0.49) | KEAP1L3MBTL1NFE2L2PTGS1PTGS2 | |
| SCHEMBL3839152 | 0.79 | NFE2L2 (0.42) | KEAP1L3MBTL1NFE2L2PTGS2KMT2A | |
| SCHEMBL29904739 | 0.79 | KEAP1 (0.65) | KEAP1L3MBTL1NFE2L2PTGS1PTGS2 | |
| SCHEMBL2068498 | 0.79 | KEAP1 (0.65) | KEAP1L3MBTL1NFE2L2PTGS1PTGS2 | |
| SCHEMBL3405309 | 0.78 | CYP19A1 (0.56) | KEAP1L3MBTL1NFE2L2PTGS1PTGS2 | |
| SCHEMBL8719438 | 0.78 | PTGS2 (0.68) | KEAP1L3MBTL1PTGS1PTGS2HSD17B10 | |
| SCHEMBL12355350 | 0.78 | KEAP1 (0.47) | KEAP1L3MBTL1NFE2L2PTGS1PTGS2 | |
| SCHEMBL22187328 | 0.78 | POLB (0.51) | HSD17B10KMT2AKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349378-A | Compounds useful as pesticides | FBC LIMITED (GB) | 1982-09-14 | — | — | US | disclosed |
| US-4309559-A | PLANT GROWTH REGULATORS AND ESPECIALLY FUNGICIDES OR HERBICIDES | FBC LIMITED (GB) | 1982-01-05 | — | — | US | disclosed |