Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.51 |
| ▸ | RXRB | P28702 | 3/20 | 0.51 |
| ▸ | RXRG | P48443 | 3/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223906 | 0.94 | RXRA (0.46) | RXRARXRBRXRGMRGPRX4RORC | |
| SCHEMBL11227267 | 0.81 | HPGD (0.48) | RXRARXRBRXRG | |
| SCHEMBL28701908 | 0.80 | RXRA (0.67) | RXRARXRBRXRGMRGPRX4RORC | |
| SCHEMBL7916728 | 0.78 | MAPT (0.48) | TTRCYP2C8AKR1C3 | |
| SCHEMBL21941770 | 0.76 | PDK2 (0.49) | RXRARXRBRXRGEPHX2TTR | |
| SCHEMBL28701907 | 0.76 | RXRA (0.56) | RXRARXRBRXRGMRGPRX4LPAR1 | |
| SCHEMBL11235065 | 0.76 | FABP4 (0.50) | RXRARXRBRXRGMRGPRX4RBP4 | |
| SCHEMBL11235067 | 0.75 | FABP4 (0.53) | RXRARXRBRXRGMRGPRX4RORC | |
| SCHEMBL28747486 | 0.74 | PTPRC (0.53) | MRGPRX4EPHX2TTRPDK2AKR1C3 | |
| SCHEMBL11227264 | 0.74 | PTK2B (0.48) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329443-A | Process for polyester-carbonate transesterifications | GENERAL ELECTRIC COMPANY (US) | 1982-05-11 | — | — | US | disclosed |