SCHEMBL11224014

SCHEMBL11224014

O=C(O)CCN1NC(c2ccccc2)OC1=S

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APEX1 P27695 1/20 0.42
▸ FABP3 P05413 1/20 0.36
▸ FABP4 P15090 1/20 0.36
▸ FABP5 Q01469 1/20 0.36
▸ MAPT P10636 2/20 0.36
▸ EGLN3 Q9H6Z9 2/20 0.35
▸ EGFR P00533 3/20 0.35
▸ KDM1A O60341 1/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CISD1 Q9NZ45 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ MAOA P21397 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11226253 0.71 APEX1 (0.42) APEX1FABP3FABP4FABP5MAPT
SCHEMBL24682250 0.63 APEX1 (0.45) APEX1FABP3FABP4FABP5MAPT
SCHEMBL11517697 0.60 APEX1 (0.42) APEX1FABP3FABP4FABP5MAPT
SCHEMBL10602038 0.60 LMNA (0.62) MEN1KMT2ALMNAMAPK1ALDH1A1
SCHEMBL4273818 0.60 APEX1 (1.00) APEX1FABP3FABP4FABP5MAPT
SCHEMBL16152867 0.60 SLC6A2 (0.33) KMT2A
SCHEMBL18836986 0.59 MEN1 (0.45) APEX1FABP3FABP4FABP5MAPT
SCHEMBL7722733 0.59 SIGMAR1 (0.75) KDM1AMEN1KMT2ALMNAALDH1A1
SCHEMBL8895595 0.59 POLB (0.38) MEN1KMT2ALMNAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL9814429 0.58 SIGMAR1 (0.73) MAPTKDM1AMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4343880-A Dye-forming electrically activatable recording material and process EASTMAN KODAK COMPANY (US) 1982-08-10 — — US disclosed
US-4201582-A MERCAPTO HETEROCYCLIC TONER, SILVER HALIDE, SILVER SALT OF CARBOXYALKYL HETEROCYCLIC THIONE, ORGANIC REDUCING AGNET EASTMAN KODAK COMPANY (US) 1980-05-06 — — US disclosed
US-4186009-A SILVER HALIDE, SILVER SALT OXIDIZING AGENT, ORGANIC REDUCING AGENT, HYDRAZINO THIOUREA NUCLEATING AGENT EASTMAN KODAK COMPANY (US) 1980-01-29 — — US disclosed
US-4168170-A NONCATALYTIC PHOTOTHERMOGRAPHY EASTMAN KODAK COMPANY (US) 1979-09-18 — — US disclosed
US-4168169-A SUBSTITUTED THIAZOLINE, OXAZOLINE, OR IMIDAZOLINE SILVER HALIDE COMPLEXING AGENT EASTMAN KODAK COMPANY (US) 1979-09-18 — — US disclosed
US-4124398-A Thiyl bleaching agents for photographic processes EASTMAN KODAK COMPANY (US) 1978-11-07 — — US disclosed
US-4123273-A WITH REDUCING AGENT, SILVER HALIDE AND ORGANIC SILVER SALT OXIDIZER; PHOTOTHERMOGRAPHY EASTMAN KODAK COMPANY (US) 1978-10-31 — — US disclosed
US-4105451-A 2-MERCAPTO-BENZOTHIAZOLE, -BENZOXAZOLE, -BENZIMIDAZOLE OR -BENZOSELENAZOLE; HETEROCYCLIC THIONE SILVER SALT; REDUCING AGENT; BINDER; SILVER HALIDE AND SENSITIZER EASTMAN KODAK COMPANY (US) 1978-08-08 — — US disclosed
US-4022617-A DIFFUSION EASTMAN KODAK COMPANY (US) 1977-05-10 — — US disclosed
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