SCHEMBL7722733

SCHEMBL7722733

O=C(O)CCN1CCC(c2ccccc2)CC1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.75
SLC18A3 Q16572 2/20 0.68
S1PR1 P21453 1/20 0.64
DRD2 P14416 2/20 0.63
KMT2A Q03164 2/20 0.62
ALDH1A1 P00352 1/20 0.62
LMNA P02545 1/20 0.62
GAA P10253 1/20 0.62
PRCP P42785 3/20 0.61
KDM1A O60341 1/20 0.60
CARM1 Q86X55 1/20 0.58
PRMT6 Q96LA8 1/20 0.58
HTR7 P34969 5/20 0.58
MEN1 O00255 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
TSHR P16473 1/20 0.56
CYP2C19 P33261 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9814429 0.98 SIGMAR1 (0.73) SIGMAR1SLC18A3S1PR1DRD2KMT2A
SCHEMBL12209841 0.92 ALDH1A1 (0.74) SIGMAR1SLC18A3S1PR1DRD2KMT2A
Hydrochloric Acid SCHEMBL9811410 0.90 ALDH1A1 (0.76) SIGMAR1SLC18A3S1PR1DRD2KMT2A
Hydrochloric Acid SCHEMBL10594777 0.89 DRD2 (0.66) SIGMAR1SLC18A3S1PR1DRD2KMT2A
SCHEMBL13589479 0.87 SIGMAR1 (0.71) SIGMAR1SLC18A3DRD2KMT2AALDH1A1
SCHEMBL18937182 0.87 SIGMAR1 (0.58) SIGMAR1SLC18A3S1PR1DRD2KMT2A
SCHEMBL12041706 0.87 S1PR1 (0.69) SIGMAR1SLC18A3S1PR1DRD2KMT2A
Hydrochloric Acid SCHEMBL10593224 0.86 HTR7 (0.70) SIGMAR1SLC18A3DRD2KMT2AALDH1A1
Hydrochloric Acid SCHEMBL9811480 0.86 HTR7 (0.70) SIGMAR1SLC18A3DRD2KMT2AALDH1A1
SCHEMBL381548 0.86 S1PR1 (0.67) SIGMAR1SLC18A3S1PR1DRD2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2025-09-25 US disclosed
US-6399631-B1 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS PFIZER INC. 2002-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP SIGMAR1 4328/4885SLC18A3 1806/4885S1PR1 4861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.