Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716783 | 0.83 | KDM4E (0.37) | ALDH1A1KDM4EMAPTHSD17B10PKM | |
| SCHEMBL28988139 | 0.83 | ADORA3 (0.34) | KDM4EPKMKMT2AMEN1HPGD | |
| SCHEMBL21358029 | 0.81 | L3MBTL1 (0.41) | ALDH1A1RAB9AKDM4ELMNAMAPT | |
| SCHEMBL1532459 | 0.76 | ALDH1A1 (0.36) | PDE3BPDE3AALDH1A1RAB9ALMNA | |
| SCHEMBL30296925 | 0.76 | ALDH1A1 (0.36) | PDE3BPDE3AALDH1A1RAB9ALMNA | |
| SCHEMBL1465555 | 0.75 | CCNB2 (0.30) | ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL277948 | 0.74 | PDE3B (0.45) | PDE3BPDE3AALDH1A1RAB9AKDM4E | |
| SCHEMBL24135848 | 0.73 | KMT2A (0.35) | PDE3BPDE3AALDH1A1RAB9APKM | |
| SCHEMBL22043212 | 0.70 | ALDH1A1 (0.38) | PDE3BPDE3AALDH1A1RAB9AKDM4E | |
| SCHEMBL11213548 | 0.70 | PDE3B (0.31) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076085-A1 | Production of monoacylpyrazines | PHILIP MORRIS INCORPORATED (US) | 1983-04-06 | — | — | EP | disclosed |