Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225698 | 0.72 | MAPT (0.43) | ALDH1A1MAPTHPGDTSHRHSD17B10 | |
| SCHEMBL13298011 | 0.72 | ACHE (0.44) | ALDH1A1KDM4EACHEBCHEGAA | |
| SCHEMBL13298030 | 0.63 | ALDH1A1 (0.44) | ALDH1A1KDM4EACHEBCHESMN1; SMN2 | |
| SCHEMBL5258391 | 0.62 | ACHE (0.42) | ALDH1A1KDM4EACHEBCHESIGMAR1 | |
| SCHEMBL4820203 | 0.61 | ACHE (0.39) | ALDH1A1KDM4EACHEBCHESIGMAR1 | |
| SCHEMBL11227402 | 0.61 | MAPT (0.46) | ALDH1A1MAPTGAASMN1; SMN2HPGD | |
| SCHEMBL10288810 | 0.61 | MEN1 (0.52) | ALDH1A1ACHEBCHESIGMAR1KDM5B | |
| SCHEMBL11223840 | 0.60 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTGAASMN1; SMN2 | |
| SCHEMBL10986805 | 0.60 | MEN1 (0.34) | ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL25230992 | 0.60 | SIGMAR1 (0.46) | ALDH1A1KDM4EACHEBCHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |