Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | POLR1A | O95602 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175314 | 0.92 | SIGMAR1 (0.42) | SIGMAR1CYP2D6CYP2C19ACHEBCHE | |
| SCHEMBL25228495 | 0.87 | CYP2D6 (0.41) | SIGMAR1CYP2D6CYP2C19ACHEBCHE | |
| SCHEMBL13298011 | 0.84 | ACHE (0.44) | SIGMAR1ACHEBCHEKDM5BALDH1A1 | |
| SCHEMBL5258395 | 0.82 | KDM4E (0.46) | SIGMAR1ACHEBCHEKDM5BALDH1A1 | |
| SCHEMBL5258391 | 0.80 | ACHE (0.42) | SIGMAR1ACHEBCHEKDM5BALDH1A1 | |
| SCHEMBL6560529 | 0.80 | ACHE (0.42) | SIGMAR1ACHEBCHEKDM5BALDH1A1 | |
| SCHEMBL10288810 | 0.78 | MEN1 (0.52) | SIGMAR1ACHEBCHEKDM5BALDH1A1 | |
| SCHEMBL10223245 | 0.77 | ACHE (0.40) | SIGMAR1ACHEBCHEKDM5BALDH1A1 | |
| SCHEMBL8504329 | 0.77 | DNM1 (0.53) | SIGMAR1ACHEBCHEALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL28704836 | 0.77 | ALDH1A1 (0.45) | SIGMAR1ACHEBCHEKDM5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118829423-A | Compositions for delivery of payload molecules to airway epithelium | 摩登纳特斯有限公司 | 2024-10-22 | — | — | CN | disclosed |
| EP-4429644-A1 | COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM | ModernaTX, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| US-20230285310-A1 | COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM | ARES CAPITAL CORPORATION, AS AGENT | 2023-09-14 | — | — | US | disclosed |
| CN-116348147-A | Compositions for delivery of payload molecules to airway epithelium | 摩登纳特斯有限公司 | 2023-06-27 | — | — | CN | disclosed |
| EP-4192433-A2 | COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM | Modernatx, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023086465-A1 | COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM | MODERNATX, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285310-A1 | COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM | CFTR, TSLP, MTREX | SIGMAR1 2761/4885CYP2D6 4850/4885CYP2C19 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.