SCHEMBL443306

SCHEMBL443306

CCOC(=O)Cc1nnn[nH]1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
LMNA P02545 1/20 0.46
HSD17B10 Q99714 3/20 0.44
RAB9A P51151 1/20 0.43
PKM P14618 1/20 0.41
ATM Q13315 1/20 0.41
CHEK1 O14757 1/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
MAPK1 P28482 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
KDM4E B2RXH2 2/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17577312 0.86 CA12 (0.41) CA12CA1CA2CA9LMNA
SCHEMBL17665568 0.83 LMNA (0.42) CA12CA1CA2CA9LMNA
SCHEMBL4123314 0.83 MAPT (0.47) CA12CA1CA2CA9LMNA
SCHEMBL9641762 0.80 CYP1A2 (0.43) CA12CA1CA2CA9HSD17B10
SCHEMBL17242958 0.79 CYP4F2 (0.44) CA12CA1CA2CA9HSD17B10
SCHEMBL28332903 0.76 POLB (0.37) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL5540795 0.75 ALDH1A1 (0.33) CA12CA1CA2CA9HSD17B10
SCHEMBL28856012 0.74 HSD17B10 (0.50) CA12CA1CA2CA9LMNA
SCHEMBL7351851 0.74 CA12 (0.32) CA12CA1CA2CA9GAA
Hydrochloric Acid SCHEMBL30428049 0.73 CA12 (0.30) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117399072-A Ultra-small cerium-based metal organic framework nano enzyme and preparation method and application thereof 华南理工大学 2024-01-16 CN claimed
CN-117106189-A Metal organic framework artificial hydrolase and preparation method and application thereof 华南理工大学 2023-11-24 CN claimed
CN-114085193-A Method for preparing 1H-tetrazoleacetic acid and derivatives thereof by aqueous phase method 九江中星医药化工有限公司 2022-02-25 CN claimed
CN-111943899-A Synthesis method of 5-ethyl formate tetrazole 河北凯力昂生物科技有限公司 2020-11-17 CN claimed
US-10196604-B2 Mitochondrial inhibitors for use in culturing pluripotent stem cells THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-02-05 US claimed
US-9918964-B2 Reducing platelet activation, aggregation and platelet-stimulated thrombosis or blood coagulation by reducing mitochondrial respiration THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2018-03-20 US claimed
US-9691951-B2 Curable silicone composition, and optical semiconductor device DOW CORNING TORAY CO., LTD. (JP) 2017-06-27 US claimed
US-20170130198-A1 MITOCHONDRIAL INHIBITORS FOR USE IN CULTURING PLURIPOTENT STEM CELLS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2017-05-11 US claimed
US-20160233395-A1 Curable Silicone Composition, And Optical Semiconductor Device DOW TORAY CO., LTD. (JP) 2016-08-11 US claimed
WO-2015196139-A1 MITOCHONDRIAL INHIBITORS FOR USE IN CULTURING PLURIPOTENT STEM CELLS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2015-12-23 WO claimed
CN-103508970-B A kind of production method of 5-tetrazoleacetic acid ethyl ester HUAFENG CHEMICAL CO., LTD., NANTONG CITY (CN) 2015-10-21 CN claimed
CN-103508970-A Ethyl 1H-tetrazole-5-acetate production method NANTONG HUAFENG CHEMICAL CO 2014-01-15 CN claimed
CN-103508969-A Synthesis production method of high-purity 1H-tetrazole-5-acetic acid NANTONG HUAFENG CHEMICAL CO 2014-01-15 CN claimed
CN-101993422-A Synthesis and application of blue-fluorescence luminous cadmium metal complex FUJIAN INST RES STR MATTER CAS 2011-03-30 CN claimed
US-20090018123-A1 Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation SINDKHEDKAR MILIND D 2009-01-15 US claimed
EP-1912980-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION Wockhardt Limited (IN) 2008-04-23 EP claimed
WO-2007023507-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION WOCKHARDT LIMITED (IN) 2007-03-01 WO claimed
US-20260099093-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED RELIEF PATTERN USING SAME, AND METHOD FOR PRODUCING POLYIMIDE FILM USING SAME ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-04-09 US disclosed
US-4258195-A Novel thiol esters and process for preparing cephalosporin compounds using same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-03-24 US disclosed
EP-0004570-A1 Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10196604-B2 Mitochondrial inhibitors for use in culturing pluripotent stem cells TFAM, TUFM, ALDH2 CA12 3688/4885CA1 2182/4885CA2 1212/4885
US-20260099093-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED RELIEF PATTERN USING SAME, AND METHOD FOR PRODUCING POLYIMIDE FILM USING SAME CD79B, ITGA1, PTK2 CA12 1676/4885CA1 204/4885CA2 833/4885
US-20090018123-A1 Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation POLL, POLM, POLRMT CA12 3371/4885CA1 3004/4885CA2 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.