SCHEMBL11224933

SCHEMBL11224933

CC1C(=O)C2(C)CCC1C(C)(C)C2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.33
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12506427 0.70 STAT1 (0.32)
SCHEMBL1172853 0.68 STAT1 (0.31)
SCHEMBL18817582 0.67 ALDH1A1 (0.41) CYP19A1
SCHEMBL18817586 0.67 ALDH1A1 (0.41) CYP19A1
SCHEMBL13244721 0.67 ALDH1A1 (0.41) CYP19A1
SCHEMBL12544194 0.60 SMN1; SMN2 (0.36)
SCHEMBL12543761 0.60 SMN1; SMN2 (0.36)
SCHEMBL30378162 0.60
SCHEMBL18393366 0.57 ALDH1A1 (0.33) CYP3A4CYP19A1
SCHEMBL11218311 0.57 LMNA (0.34) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4320771-A Use of 2-oxabicyclooctane derivative in augmenting or enhancing the aroma or taste of smoking tobaccos and smoking tobacco articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-03-23 US disclosed